Six Indiana University Bloomington researchers have received grants from a program that supports developing translational research projects; offered by the Johnson Center for Innovation and Translational Research. Dr. Hui-Chen Lu received $25,000 to develop “Preclinical studies to evaluate RNA-based therapeutic agents for reducing neurodegeneration,". The goal of the project is to identify biomarkers that assess the efficacy of agents in modulating neuroinflammatory responses. These agents could slow down neurodegenerative conditions like Alzheimer's disease.
Our recent work revealing the power of micro-RNA as potential bio-markers for Alzheimer’s disease was recently featured on CBS 4 - Indianapolis.
Our latest scientific paper published in Nature Scientific Reports has shown that microRNAs might work as biomarkers for Alzheimer's disease. Identifying biomarkers early in a disease is important for diagnosing the condition, and following its progression and response to treatment. Follow the link below to read the full article.
Congratulations to Miss Jessica Felker for receiving the "Women in STEM Summer Research Fellowship"! She will do research in the Lu Lab during the summer, and will present her results in a poster session on July 26 at the Simon Skjodt Assembly Hall.
Jessica, we are so proud of you!!
At IU's Gill Center for Biomolecular Science, a research dream team tackles neuroscience's toughest challenges.
In our latest publication, a large-scale discovery assay was used to identify factors that increases NMNAT2 levels in the brain. One of those compounds was caffeine, and it has drawn some attention!
In the most recent publication from the Lu Laboratory in Scientific Reports, various compounds were screened for their effect on NMNAT2 levels -- a protein we previously identified for its protective role in Alzheimer's disease. Graduate student Gillian Bradley and assistant faculty Dr. Yousuf Ali were the primary contributors to the project with Dr. Hui-Chen Lu.
On December, 7th, Dr. Hui-Chen Lu, Dr. Yousuf Ali, and Hunter Allen were featured on Reddit as a part of the /r/science "Ask Me Anything" series, where they answered questions from users around the world regarding their recently published work on NMNAT2 in PLoS Biology.
We've just published a new paper in The Journal of Neuroscience describing the role of mGluR5 in cortical neuron development. Follow the link below to read the full article.
The American Federation for Aging Research chose to highlight a few of our collaborators, Dr. Giulio Taglialatela and Dr. Joshua Shulman, for their contributions to our most recent publication in PLOS Biology.