Hui-Chen Lu, is a Gill Chair of Neuroscience in the Department of Psychological and Brain Sciences at Indiana University. She received her Ph.D. from Baylor College of Medicine, Houston. Her research focuses on the signaling cascades underlying neural circuit connections during brain development, to understand how sensory experiences affect neural circuit wiring, and to identify novel factors required to maintain the health of neural circuits during aging.
B.S., National Taiwan University, 1991
Ph.D., Baylor College of Medicine, 1997
Postdoctoral Fellow, Baylor College of Medicine, 1997-2003
Development of cortical neural circuits, in particular on activity-dependent remodeling and how to correct mis-wiring in neurological disorders.
Neuroprotective strategies to reserve cognition and to protect against dementia.
The role of FGF/FGFR signaling in brain circuitry formation and maintenance.
The underlying mechanisms that regulate FGF/FGFR expression.
Izaque de Sousa Maciel is a postdoctoral fellow in the Department of Psychological and Brain Sciences at Indiana University. He received his Ph.D. from the Department of Pharmacology of the School of Medicine of Ribeirao Preto - University of Sao Paulo, Brazil. He has investigated the role of immune-inflammatory processes and stress in the depression-like behavior in rodents. He is currently investigating the role of stress on neuron morphology using multi-photon microscopy in awake mice.
B.S. in Pharmacy, Pontificia Universidade Catolica do Rio Grande do Sul, Brazil, 2012
M.S. in Medicine and Science of Health with emphasis on Pharmacology and Biochemistry, Pontificia Universidade Catolica do Rio Grande do Sul, Brazil, 2014
Ph.D. visiting student, Neuroscience Center, University of Helsinki, 2016-2017
Ph.D. in Pharmacology, Ribeirao Preto Medical School, University of Sao aulo, Brazil, 2018
Sen Yang is a dual Ph.D. student in Psychology & Brain Sciences and Neuroscience at Indiana University Bloomington. Her research interest is in neurodegenerative disease, specifically in the synaptic loss associated with Alzheimer's disease, and mechanisms of learning, memory, and consciousness.
Zhen Xian is a Ph.D. student from Taiwan. His research interest is in neural circuitry and development. He assists with cryosectioning and staining in the lab. He is also learning patch clamp and will try to use this technique for further research.
B.S., National Taiwan Ocean University, 2012
Gabriel is a P.h.D student from Brazil admitted to the Program in Neuroscience. During his undergraduate course in Brazil at the Pharmacy-Biochemistry School at the University of São Paulo, Gabriel’s work included a rodent animal model of Parkinson’s disease, pharmacological manipulation of the dopaminergic system, and neuroinflammation. His current project at the Lu lab concerns the development of astrocytes and their interactions with the cannabinoids system. Gabriel is focused on learning more about imaging acquisition techniques using confocal and 2-Photon microscopes and how to analyze 3D fluorescent cells. His favorites hobbies include running and outdoor activities with friends.
Romario is from São Paulo, Brazil. He studied at Mackenzie Presbyterian University and majored in Biology, and received his teaching certificate in Biological Sciences. His previous research in Brazil pertains to the influence of a chronic fructose diet on the autonomic cardiac function. At Wright State University in Dayton, Ohio, he was a part of collaborative work on the expression and location of NKCCs cotransporters in the cell. In the Lu lab he has contributed by analyzing specimen behavior and lab maintenance.
B.S. in Biological Sciences, Mackenzie Presbyterian University, Brazil, 2014
Undergraduate & High-School Students
Jie-En Wu is an undergraduate majoring in Neuroscience. She has been in the Lu Lab since 2016, working in mice management. Currently, she is also assisting the research of Dr. Jonathon Crystal. Additionally, she is a member of Alpha Chi Sigma, as well as the Longboarding Club.
Theo Knowles is an undergraduate studying Microbiology with respect to the brain. He comes from Columbus, Ohio and enjoys playing soccer and going on hikes. In the Lu Lab, he is working with Dr. Maciel on his project elucidating the effects of prenatal CBD and THC exposure.
Xuan is an undergraduate majoring in Neuroscience. He is fascinated by neurodevelopment and what can go wrong during the process. In the Lu Lab, he is currently working under the supervision of Dr. Jui-Yen Huang to reconstruct dendritic spines in FGF and FGFR knockout mice.
Rida is majoring in neuroscience and biotechnology with minors in chemistry and french. She is very interested in the relationship between music and the brain, and published a paper on the topic in May 2019. In Dr. Lu’s lab, she currently works on studying the effects of cannabinoids in mice to better understand potential effects in humans.
Caliel is a premedical student majoring in Neuroscience with potential minors in Biotechnology, Chemistry, and Psychology. His interests include playing guitar, basketball, and reading the Bible. He has not been tasked with an official research assignment just yet, but is very interested in the research questions: How do neuronal circuits form in the developing brain? (mGluR5, synaptic plasticity, the endogenous cannabinoid system) and how is a healthy brain maintained and what causes neurons to die? (NMNAT2, therapeutic interventions). He hopes to understand the brain's ability to grow, reform, and what can help improve these stages.
Former Lab Members
Honorary Lab Members
Trisha and Jana are the core administrators for the Gill Center and, with their invaluable assistance, have made the research of the all of the Gill Center laboratories possible.
Rick and Jesse head-up the workshop for the psychology department. They have helped in numerous ways, including lab modifications to facilitate our work and manufacture of custom tools and prototypes that aid in our ongoing research projects.