Principal Investigator

Hui-Chen Lu, is a Gill Chair of Neuroscience in the Department of Psychological and Brain Sciences at Indiana University. She received her Ph.D. from Baylor College of Medicine, Houston. Her research focuses on the signaling cascades underlying neural circuit connections during brain development, to understand how sensory experiences affect neural circuit wiring, and to identify novel factors required to maintain the health of neural circuits during aging.

Education:

  • B.S., National Taiwan University, 1991
  • Ph.D., Baylor College of Medicine, 1997
  • Postdoctoral Fellow, Baylor College of Medicine, 1997-2003

Current Research:

  • Development of cortical neural circuits, in particular on activity-dependent remodeling and how to correct mis-wiring in neurological disorders.
  • Neuroprotective strategies to reserve cognition and to protect against dementia.

ASSISTANT SCIENTISTS

Jui-Yen Huang, Ph.D. juiyhuan@iu.edu Curriculum Vitae

Current Research:

  • The role of FGF/FGFR signaling in brain circuitry formation and maintenance.
  • The underlying mechanisms that regulate FGF/FGFR expression.

Post-Doctoral Fellows

Salil Sharma, Ph.D. salishar@iu.edu Curriculum Vitae

Salil Sharma is a postdoctoral fellow in the Department of Psychological and Brain Sciences at Indiana University. He received his Ph.D. from University of Miami School of Medicine. He has a long-standing interest in exploring the role of microRNAs and other non-coding regulatory molecules in various diseases. He is currently pursuing the possibility to use circulating microRNAs as biomarkers as well as therapeutic targets for neurodegenerative diseases including Alzheimer’s disease (AD).

Education:

  • M.S., Bangalore University, India 2003
  • Ph.D., University of Miami School of Medicine, 2011
  • Postdoctoral Fellow, University of California Los Angeles, 2012-2015

Current Research:

  • Study the mechanistic role of noncoding RNA molecules, in particular, circulating microRNAs as regulatory molecules that contribute to the onset and progression of AD.
  • Identify circulating miRNAs that are altered in early AD, and could ultimately and reliably be used as biomarkers to monitor pathological changes in AD patients.

Graduate Students

Sen Yang is a dual Ph.D. student in Psychology & Brain Sciences and Neuroscience at Indiana University Bloomington. Her research interest is in neurodegenerative disease, specifically in the synaptic loss associated with Alzheimer's disease, and mechanisms of learning, memory, and consciousness.

 

Research Technicians

Bruce Henry bhenry@iupui.edu

Bruce Henry

bhenry@iupui.edu

Bruce joined the Lu laboratory after working for many years in the microscopy core at Indiana University-Purdue University Indianapolis. He now assists with both surgical procedures and in vivo multi-photon microscopy. His hobbies are canoeing, backpacking, camping, fishing, geology, and wood working.

Education:

  • B.S., University of Indianapolis, 1973
 
Bruna Krebs Kutche baumgarb@indiana.edu

Bruna Krebs Kutche

baumgarb@indiana.edu

Bruna is a Research Technician from Rio de Janeiro, Brazil. She studied at UNIRIO - Federal University of the State of Rio de Janeiro, and majored in Biology. She has previously done research in Bioinformatics. In the Lu Lab, she is responsible for the multi-photon microscope operation, performing in vitro, in vivo, and eventually awake behaving imaging studies. She also performs data analysis and manages the lab IT functions.

Education:

  • B.S. in Biology, UNIRIO - Federal University of the State of Rio de Janeiro, Brazil, 2016
 
Zhen Xian Niou niouz@iu.edu

Zhen Xian Niou

niouz@iu.edu

Zhen Xian is a Research Technician from Taiwan. His research interest is in neural circuitry and development. He assists with cryosectioning and staining in the lab. He is also learning patch clamp and will try to use this technique for further research. 

Education:

  • B.S., National Taiwan Ocean University, 2012
 
Romario Pacheco Andrade ropache@iu.edu Curriculum Vitae

Romario Pacheco Andrade

ropache@iu.edu

Curriculum Vitae

Romario is from São Paulo, Brazil. He studied at Mackenzie Presbyterian University and majored in Biology, and received his teaching certificate in Biological Sciences. His previous research in Brazil pertains to the influence of a chronic fructose diet on the autonomic cardiac function. At Wright State University in Dayton, Ohio, he was a part of collaborative work on the expression and location of NKCCs cotransporters in the cell. In the Lu lab he has contributed by analyzing specimen behavior and lab maintenance.

Education:

  • B.S. in Biological Sciences, Mackenzie Presbyterian University, Brazil, 2014

Undergraduate & High-School Students

Tiffany Xie tifxie@indiana.edu

Tiffany Xie is an undergraduate studying Biology and English. She joined the Lu Lab in 2017 with a focus on Molecular Biology. She writes for the Indiana University Journal of Undergraduate Research blog and is a violist in the Bloomington Symphony Orchestra. Her current project involves examining neurodevelopmental changes in mGluR5 conditional knockout mice.

 
Jessica Felker jrfelker@indiana.edu

Jessica Felker

jrfelker@indiana.edu

Jessica is a Freshman at Indiana University, and plan to pursue a degree in Neuroscience. She is from Indianapolis, where she graduated from Nexus Academy. She has conducted research as a high school student at Riley Hospital in Ophthalmology, as well as at Eli Lilly in Diabetes. Her career goal is to become a pediatric surgeon as well as continue in research.
 

 

Jie-En Wu is an undergraduate majoring in Neuroscience. She has been in the Lu Lab since 2016, working in mice management. Currently, she is also assisting the research of Dr. Jonathon Crystal. Additionally, she is a member of Alpha Chi Sigma, as well as the Longboarding Club.

 

Adam is currently pursuing majors in both Biology and Spanish. He is a Senior and a Pre-Med student as well. Currently he is applying to the Indiana University School of Medicine and hopes to attend starting in the Fall of 2018. In the lab he assists Dr. Salil Sharma with his work with mir142.

 
Eamonn Duffy epduffy@umail.iu.edu

Eamonn is an undergraduate studying Neuroscience and Chemistry. He joined the lab in 2017, and is interested in how memories are formed at the molecular level. Eamonn is a co-captain of the Hutton Connections Science & Research Huddle and is a member of the Hutton Ethics Planning Committee. Outside of academia, Eamonn enjoys playing piano and cooking.


Former Lab Members

Gillian Bradley gillian.m.bradley@gmail.com Currently at Penn FTD Center

Gillian Bradley
gillian.m.bradley@gmail.com

Currently at Penn FTD Center

Dena B. Mahmoudi denabakh@indiana.edu  

Dena B. Mahmoudi
denabakh@indiana.edu

 

Jason Graf jasongraf6@yahoo.com Currently at IU School of Medicine

Jason Graf
jasongraf6@yahoo.com

Currently at IU School of Medicine

Marisha Miskus mmiskus@imail.iu.edu  

Marisha Miskus
mmiskus@imail.iu.edu

 

Carlos Ballester cb143163@bcm.edu Currently at Baylor College of Medicine

Carlos Ballester
cb143163@bcm.edu

Currently at Baylor College of Medicine

Jie Zhu zhujie.usa@hotmail.com Currently at Baylor Genetics Lab

Jie Zhu
zhujie.usa@hotmail.com

Currently at Baylor Genetics Lab

Yousuf Ali  

Yousuf Ali
 

Chris Jew

Chris Jew

Chia-Shan Wu cjwu@tamu.edu Currently at Texas A&M University

Chia-Shan Wu
cjwu@tamu.edu

Currently at Texas A&M University

Cecilia Ljungberg

Cecilia Ljungberg

Hunter Allen allenhm@gmail.com  

Hunter Allen
allenhm@gmail.com

 

Michael Hess mhess21@students.claremontmckenna.edu Currently at Claremont McKenna College

Michael Hess
mhess21@students.claremontmckenna.edu

Currently at Claremont McKenna College


Honorary Lab Members

Misty Theodore

Misty Theodore

Jana England

Jana England

Misty and Jana are the core administrators for the Gill Center and, with their invaluable assistance, have made the research of the all of the Gill Center laboratories possible.

 
Richard Moore

Richard Moore

Jesse Goode

Jesse Goode

Rick and Jesse head-up the workshop for the psychology department. They have helped in numerous ways, including lab modifications to facilitate our work and manufacture of custom tools and prototypes that aid in our ongoing research projects.